任晓亮,汉族,中共党员,中药学博士,教授,博士生导师。博士毕业于威尼斯人app中医药大学中药学专业,获医学博士学位,现任威尼斯人app党委书记。
主要从事基于化学计量学的中药质量控制、基于生物药剂学的中药配伍理论研究。主讲本科生《威尼斯人app》,硕士研究生《威尼斯人app下载》《威尼斯人app》,博士研究生《威尼斯人app》等课程。主持国家自然科学基金面上项目4项,国家自然科学基金青年基金1项、教育部高等学校博士学科点专项科研基金新教师基金1项,国家中药标准化项目分项目1项,威尼斯人app市教委科研计划项目重点项目1项。以第一作者或通讯作者发表论文100余篇,其中SCI收录论文50篇、被引700余次。主编中药学-药学研究生系列教材1部,参编全国高等中医药院校规划教材2部。作为主要发明人申请专利27项,获专利授权17项。威尼斯人app市创新人才推进计划中青年科技创新领军人才,威尼斯人app市“131”创新型人才培养工程第二层次人选。中药学市级实验教学示范中心(威尼斯人app中医药大学)主任,威尼斯人app市级课程思政示范课程《威尼斯人app下载》课程负责人,威尼斯人app中医药大学分析化学教学团队负责人,2020年获威尼斯人app市科学技术进步三等奖(排名第1),2022年获得威尼斯人app市教学成果特等奖1项(排名第8)、一等奖1项(排名第4)。
承担科研项目情况:
[1] 国家自然科学基金青年基金“基于降解网络模式的中药注射剂(血必净)安全性再评价新方法”(81102732),22万元,2012.1-2014.12。(主持)
[2] 教育部高等学校博士学科点专项科研基金新教师基金“基于降解网络模式的中药注射剂质量评价新方法”(20111210120006),4万元,2012.1-2014.12。(主持)
[3] 国家自然科学基金面上项目“基于生物药剂学无标度复杂网络模式的中药复方(血脂宁)配伍的分子作用机制研究”(81473543),72万元,2015.01-2018.12。(主持)
[4] 国家中药标准化项目“蓝芩口服液标准化建设”(ZYBZH-C-JS-29)分项目:蓝芩口服液指纹图谱及质量标准研究,125万元,2016.1-2018.12。(主持)
[5] 国家自然科学基金面上项目“基于生物药剂学可视化人工神经网络模式的“甘味”中药(甘草)“能缓能和”配伍作用的分子机制研究”(81774149),60万元,2018.01-2021.12。(主持)
[6] 国家自然科学基金面上项目“基于“时-空”环境刺激响应修饰定量生物药剂学分类系统的中药复方(麻杏石甘汤)配伍机制研究新方法”(82074280),65万元,2021.01-2024.12。(主持)
[7] 威尼斯人app市教委科研计划项目重点项目“基于“成分-物态-效应”交互作用主动学习框架的中药复方配伍机制研究新方法——以宣肺败毒方为例”(2021ZD009),20万元,2022.01-2024.12。(主持)
[8] 国家自然科学基金面上项目“基于"TPH1/MAO-A/5-HT/5-HT3R轴结合物态效应探讨宣肺败毒方"培土生金”干预消化道功能治疗新冠肺炎作用及配伍机制研究”(82274236), 52万元, 2023.01-2026.12。(主持)
主要代表性成果:
1. Na Li, Guoqin Zhang, Xueyan Zhang, Yi Liu, Yan Kong, Meng Wang*, Xiaoliang Ren*. A rapid-floating natural polysaccharide gel–raft with double-effect for the treatment of gastroesophageal reflux disease. International Journal of Biological Macromolecules. 2024, 261(8): 129667. (中国科威尼斯人app一区)
2. Yu Yin#, Zhen Yang#, Na Li, Xuan Yu, Meiling Chen, Meng Wang*, Xiaoliang Ren*. Least absolute shrinkage and selection operator-based prediction the binding constant of p-sulfonatocalix[6]\/[8]arenes with alkaloids. Journal of Chemical Information and Modeling. 2024, 64(2): 359-377. (中国科威尼斯人app二区TOP)
3. Na Li, Guoqin Zhang, Yi Liu, Lili Sun, Xin Zhao, Liqin Ding, Yanan Liu*, Meng Wang*, Xiaoliang Ren*. A Natural Self-assembled Gel-sponge with Hierarchical Porous Structure for Rapid Hemostasis and Antibacterial. Advanced Healthcare Materials. 2023, 12(28): e2301465. (中国科威尼斯人app二区TOP)
4. Lili Sun#, Guangjiao You#, Fuxiang Zheng, Meng Wang, Xiaoliang Ren*, Yanru Deng. In vitro and in vivo evaluation of the influences of polysaccharides derived from Glycyrrhiza uralensis on three alkaloids and potential interaction mechanisms. International Journal of Biological Macromolecules. 2020, 157: 452-460. (中国科威尼斯人app一区)
5. Fan Liu#, Lili Sun#, Guangjiao You, Han Liu, Xiaoliang Ren*, Meng Wang*. Effects of Astragalus polysaccharide on the solubility and stability of 15 flavonoids. International Journal of Biological Macromolecules, 2020, 143: 873-880. (中国科威尼斯人app一区)
6. Huanhuan Li, Xuexiao Cao, Yanan Liu, Tingting Liu, Meng Wang*, Xiaoliang Ren*, Zhiying Dou. Establishment of modified biopharmaceutics classification system absorption model for oral Traditional Chinese Medicine (Sanye Tablet). Journal of Ethnopharmacology, 2019, 244(15): 112148. (中国科威尼斯人app二区TOP)
7. Lili Sun, MengWang, Huijie Zhang, Guangjiao You, Yanan Liu, Xiaoliang Ren*, Yanru Deng. The influence of polysaccharides from Ophiopogon japonicus on 2,3,5,4′-tetrahydroxy-stilbene-2-O-β-d-glucoside about biopharmaceutical properties in vitro and pharmacokinetics in vivo. International Journal of Biological Macromolecules, 2018, 119: 677-682. (中国科威尼斯人app一区)
8. Guangjiao You, Lili Sun, Xuexiao Cao, Huanhuan Li, Meng Wang, Yanan Liu, Xiaoliang Ren*. Comprehensive evaluation of solubilization of flavonoids by various cyclodextrins using high performance liquid chromatography and chemometry. LWT-Food Science and Technology, 2018, 94: 172-177. (中国科威尼斯人app一区)
9. Huijie Zhang, Meng Wang, Lina Chen, Yanan Liu, Han Liu, Hongna Huo, Lili Sun, Xiaoliang Ren*, Yanru Deng, Aidi Qi. Structure-solubility relationships and thermodynamic aspects of solubility of some flavonoids in the solvents modeling biological media. Journal of Molecular Liquids, 2017, 225: 439-445. (中国科威尼斯人app二区TOP)
10. Huijie Zhang, Yanan Liu, Meng Wang, Yuefei Wang, Yanru Deng, Minglei Cui, Xiaoliang Ren*, Aidi Qi. One-pot β-cyclodextrin-assisted extraction of active ingredients from Xue–Zhi–Ning basing its encapsulated ability. Carbohydrate Polymers, 2015, 132(11): 437-443. (中国科威尼斯人app一区)
威尼斯人app:xiaoliang_ren@sina.com